KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LIG3
All Species:
19.39
Human Site:
T388
Identified Species:
35.56
UniProt:
P49916
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49916
NP_002302.2
1009
112907
T388
L
L
R
L
S
K
L
T
K
E
D
E
Q
Q
Q
Chimpanzee
Pan troglodytes
XP_511409
922
102716
A353
L
D
P
N
A
Y
E
A
F
K
A
S
R
N
L
Rhesus Macaque
Macaca mulatta
XP_001113780
1009
112805
T388
L
L
R
L
S
R
L
T
K
E
D
E
Q
Q
Q
Dog
Lupus familis
XP_548265
991
110592
T389
L
L
Q
L
S
K
L
T
K
E
D
E
Q
Q
Q
Cat
Felis silvestris
Mouse
Mus musculus
P97386
1015
113000
T393
L
L
H
L
S
K
L
T
K
E
D
E
Q
Q
Q
Rat
Rattus norvegicus
NP_001012011
943
105425
L373
F
P
P
A
A
K
S
L
L
T
I
Q
E
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001006215
902
101303
M333
L
I
K
H
D
L
K
M
N
A
G
A
K
H
V
Frog
Xenopus laevis
NP_001082183
988
110688
T353
L
T
R
L
S
K
M
T
K
E
E
D
Q
Q
N
Zebra Danio
Brachydanio rerio
NP_001025345
752
84159
C183
L
R
E
F
R
K
L
C
A
L
V
A
E
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650187
806
90830
P237
N
K
N
Y
A
S
S
P
V
K
K
T
K
K
T
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q27474
773
86292
T204
A
F
T
L
S
K
I
T
D
Q
K
V
R
G
D
Sea Urchin
Strong. purpuratus
XP_786357
875
97201
K306
D
N
M
S
M
M
T
K
E
L
E
Q
Q
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P04819
755
84810
L186
M
K
Q
S
S
K
N
L
I
P
T
T
Y
L
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91.1
97.7
89.4
N.A.
87.3
82.4
N.A.
N.A.
71.3
68.2
55.7
N.A.
34.9
N.A.
23.3
48.4
Protein Similarity:
100
91.1
98.8
92.2
N.A.
91.3
86.4
N.A.
N.A.
78.9
79.6
64.9
N.A.
48.1
N.A.
39.3
62.9
P-Site Identity:
100
6.6
93.3
93.3
N.A.
93.3
6.6
N.A.
N.A.
6.6
66.6
20
N.A.
0
N.A.
26.6
6.6
P-Site Similarity:
100
26.6
100
100
N.A.
93.3
26.6
N.A.
N.A.
26.6
86.6
33.3
N.A.
26.6
N.A.
46.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
20.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
35.4
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
24
0
0
8
8
8
8
16
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
8
0
0
0
8
0
31
8
0
0
16
% D
% Glu:
0
0
8
0
0
0
8
0
8
39
16
31
16
0
8
% E
% Phe:
8
8
0
8
0
0
0
0
8
0
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
0
0
8
0
% G
% His:
0
0
8
8
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
0
8
0
0
0
0
8
0
8
0
8
0
0
0
0
% I
% Lys:
0
16
8
0
0
62
8
8
39
16
16
0
16
16
0
% K
% Leu:
62
31
0
47
0
8
39
16
8
16
0
0
0
8
8
% L
% Met:
8
0
8
0
8
8
8
8
0
0
0
0
0
0
0
% M
% Asn:
8
8
8
8
0
0
8
0
8
0
0
0
0
8
8
% N
% Pro:
0
8
16
0
0
0
0
8
0
8
0
0
0
0
0
% P
% Gln:
0
0
16
0
0
0
0
0
0
8
0
16
47
39
31
% Q
% Arg:
0
8
24
0
8
8
0
0
0
0
0
0
16
8
0
% R
% Ser:
0
0
0
16
54
8
16
0
0
0
0
8
0
0
8
% S
% Thr:
0
8
8
0
0
0
8
47
0
8
8
16
0
0
8
% T
% Val:
0
0
0
0
0
0
0
0
8
0
8
8
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _